Table 5 Association of Her2 neu expression with clinicopathologic parameters in prostatic acinar adenocarcinoma
n(%) | P-Value | |||
|---|---|---|---|---|
Positive (n = 28) | Negative (n = 95) | |||
Age Group | ≤70 years | 16(57.1) | 61(64.2) | 0.497 |
> 70 years | 12(42.9) | 34(35.8) | ||
Total gleason score | 6 | 4(14.3) | 35(36.8) | 0.029 |
7 | 5(17.9) | 24(25.3) | ||
8 | 8(28.6) | 19(20) | ||
9 | 11(39.3) | 17(17.9) | ||
WHO grade groupª | Grade 1 | 4(14.3) | 35(36.8) | 0.014 |
Grade 2 | 3(10.7) | 22(23.2) | ||
Grade 3 | 2(7.1) | 2(2.1) | ||
Grade 4 | 8(28.6) | 19(20) | ||
Grade 5 | 11(39.3) | 17(17.9) | ||
Tumor Quantification | < 10% | 3(10.7) | 20(21.1) | 0.028 |
10–50% | 4(14.3) | 31(32.6) | ||
> 50% | 21(75) | 44(46.3) | ||
Perineural invasion | Present | 14(50) | 32(33.7) | 0.117 |
Absent | 14(50) | 63(66.3) | ||
Lymphovascular invasionª | Present | 0(0) | 3(3.2) | 1.000 |
Absent | 28(100) | 92(96.8) | ||
Extraprostatic extensionª | Present | 0(0) | 7(7.4) | 0.349 |
Absent | 28(100) | 88(92.6) | ||
Seminal vesicle invasion ª | Present | 2(7.1) | 2(2.1) | 0.222 |
Absent | 26(92.9) | 93(97.9) | ||
Recurrence | Yes | 19(67.9) | 14(14.7) | < 0.001 |
No | 9(32.1) | 81(85.3) | ||
EGFR | Positive | 8(28.6) | 92(96.8) | < 0.001 |
Negative | 20(71.4) | 3(3.2) | ||