Skip to main content

Table 3 Expression of the proteins studied by immunohistochemistry and association with tumor site of oral carcinomas

From: Prognostic implications of the phosphatidylinositol 3-kinase/Akt signaling pathway in oral squamous cell carcinoma: overexpression of p-mTOR indicates an adverse prognosis

Variable

Category

TUMOR SITE

Total

N° (%)

P value

Gingival

N° (%)

Hard Palate

N° (%)

Alveolar ridge

N° (%)

PI3K

Negative

2 (6.7)

2 (6.9)

5 (8.3)

9 (7.6)

0.949

Positive

28 (93.3)

27 (93.1)

55 (91.7)

110 (92.4)

p-mTOR cytoplasm

Negative

2 (6.7)

5 (16.7)

7 (11.9)

14 (11.8)

0.485

Positive

28 (93.3)

25 (83.3)

52 (88.1)

105 (88.2)

p-mTOR membrane

Negative

15 (50.0)

22 (73.3)

29 (49.2)

66 (55.5)

0.075

Positive

15 (50.0)

8 (26.7)

30 (50.8)

53 (44.5)

p-mTOR nuclei

Negative

17 (56.7)

13 (43.3)

38 (64.4)

68 (57.1)

0.164

Positive

13 (43.3)

17 (56.7)

21 (35.6)

51 (42.9)

p-AKT cytoplasm

Negative

2 (6.7)

0 (0.0)

5 (8.3)

7 (5.8)

0.275

Positive

28 (93.3)

30 (100.0)

55 (91.7)

113 (94.2)

p-AKT nuclei

Negative

12 (40.0)

10 (33.3)

21 (35.0)

43 (35.8)

0.850

Positive

18 (60.0)

20 (66.7)

39 (65.0)

77 (64.2)

p-MAPK cytoplasm

Negative

2 (6.7)

3 (10.0)

9 (15.0)

14 (11.7)

0.483

Positive

28 (93.3)

27 (90.0)

51 (85.0)

106 (88.3)

p-MAPK nuclei

Negative

11 (36.7)

15 (50.0)

24 (40.0)

50 (41.7)

0.539

Positive

19 (63.3)

15 (50.0)

36 (60.0)

70 (58.3)