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Fig. 5 | Applied Cancer Research

Fig. 5

From: What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs

Fig. 5

a GCNIS is a proliferation of intratubular malignant germ cells with morphologic and immunohistochemical features of seminoma cells arising in the spermatogonial niche; note also the presence of intertubular infiltrating seminoma. b IHC by C-kit (CD117) highlights the GCNIS in the tubules and in the interstitium

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